Pubblicazioni

Autori:

Rabiolo, A; Zucchiatti, I; Marchese, A; Baldin, G; Sacconi, R; Montorio, D; Cicinelli, M. V; Querques, L; Bandello, F; Querques, G.

Titolo:

Multimodal retinal imaging in central serous chorioretinopathy treated with oral eplerenone or photodynamic therapy

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

EYE

ISSN Rivista:

0950-222X

N° Volume:

32

Numero o Fascicolo:

1

Intervallo pagine:

55-66

Parole chiave:

optical coherence tomography; optical coherence tomography angiography; central serous chorioretinopathy; eplerenone; half-fluence photodynamic therapy; treatment

Breve descrizione dei contenuti:

Purpose: To correlate function and structural optical coherence tomography (OCT) to optical coherence tomography angiography (OCT-A) measures in patients affected by central serous chorioretinopathy (CSC) and to describe their changes after treatments (ie oral eplerenone, half-fluence photodynamic therapy (PDT)). Patients and methods: Twenty eyes of 16 consecutive patients with treatment-naïve CSC undergoing either eplerenone or PDT were enrolled in this prospective, observational study. All patients underwent structural OCT and OCT-A at baseline and after therapy at months 1 and 3. Results: Eleven eyes of nine patients and nine eyes of seven patients underwent eplerenone or PDT treatment, respectively. Central macular thickness (CMT) and subretinal fluid (SRF) correlated to fovea avascular zone (FAZ) area (r=0.74 and r=0.71, P=0.01) and vessel density (r=0.77 and r=0.68, P=0.01) at deep capillary plexus (DCP). CMT (P=0.0011), SRF (P=0.0005), SFCT (P=0.0016), FAZ area at DCP (P=0.0334) improved at 3-month visit. A significant reduction of deep FAZ area was appreciated in eplerenone (P=0.0204) but not in PDT (P=0.5) group. SFCT reduction was significantly higher in PDT than eplerenone group (P=0.0347). Conclusion: Structural and vascular parameters are correlated in CSC and they improve after different treatments. Both half-fluence PDT and oral eplerenone do not permanently damage choriocapillaris or other choroidal layers as evaluated by OCT-A.

Pagina Web:

https://doi.org/10.1038/eye.2017.290

Id prodotto:

100102

Handle IRIS:

11562/972201

ultima modifica:

14 novembre 2022

Citazione bibliografica:

Rabiolo, A; Zucchiatti, I; Marchese, A; Baldin, G; Sacconi, R; Montorio, D; Cicinelli, M. V; Querques, L; Bandello, F; Querques, G., Multimodal retinal imaging in central serous chorioretinopathy treated with oral eplerenone or photodynamic therapy «EYE» , vol. 32 , n. 1 , 2018 , pp. 55-66

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