Pubblicazioni

Autori:

Sbrana, Francesco; Sozio, Emanuela; Bassetti, Matteo; Ripoli, Andrea; Pieralli, Filippo; Azzini, Anna Maria; Morettini, Alessandro; Nozzoli, Carlo; Merelli, Maria; Rizzardo, Sebastiano; Bertolino, Giacomo; Carrara, Davide; Scarparo, Claudio; Concia, Ercole; Menichetti, Francesco; Tascini, Carlo

Titolo:

Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

INTERNAL AND EMERGENCY MEDICINE

ISSN Rivista:

1828-0447

N° Volume:

13

Numero o Fascicolo:

2

Intervallo pagine:

199-204

Parole chiave:

Candidemia; Chronic kidney failure; Internal medicine wards; Sepsis; Septic shock; Steroid therapy

Breve descrizione dei contenuti:

Candida is an increasing cause of bloodstream infection and is associated with significant morbidity and mortality. The aim of our study is to analyze risk factors for short-term mortality in patients with bloodstream Candida spp. infections admitted to Internal Medicine Wards (IMWs). This was a retrospective case-control study between January 2012 and December 2014 from four University Hospitals in Italy, where patients with candidemia dying within 30 days from diagnosis were matched to control cases with candidemia who survived in the same period of time. Two-hundred and fifty cases of candidemia were registered during the 36 months of enrollment. Among these, 112 patients died (45%) within 30 days from the first blood culture's positivity for Candida spp. At multivariate analysis, septic shock [odds ratio (95% CI) = 2.919 (1.62-5.35), p < 0.001] and concomitant chronic kidney failure [odds ratio (95% CI) = 2.296 (1.07-5.12), p = 0.036] were independent predictors of mortality. Low-dose chronic steroid therapy was protective [odds ratio (95% CI) = 0.461 (0.25-0.83), p = 0.011).

Id prodotto:

100079

Handle IRIS:

11562/972261

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Sbrana, Francesco; Sozio, Emanuela; Bassetti, Matteo; Ripoli, Andrea; Pieralli, Filippo; Azzini, Anna Maria; Morettini, Alessandro; Nozzoli, Carlo; Merelli, Maria; Rizzardo, Sebastiano; Bertolino, Giacomo; Carrara, Davide; Scarparo, Claudio; Concia, Ercole; Menichetti, Francesco; Tascini, Carlo, Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards «INTERNAL AND EMERGENCY MEDICINE» , vol. 13 , n. 2 , 2018 , pp. 199-204

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