Publications

Authors:

Querques, Giuseppe; Cicinelli, Maria Vittoria; Rabiolo, Alessandro; de Vitis, Luigi; Sacconi, Riccardo; Querques, Lea; Bandello, Francesco

Title:

Laser photocoagulation as treatment of non-exudative age-related macular degeneration: state-of-the-art and future perspectives

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

Graefes Archive for Clinical and Experimental Ophthalmology

ISSN of journal:

0721-832X

N° Volume:

256

Number or Folder:

1

Page numbers:

1-9

Keyword:

Age-related macular degeneration; Laser photocoagulation; Reticular pseudodrusen; Subthreshold laser

Short description of contents:

PURPOSE: To give an updated review of laser approaches to non-exudative age-related macular degeneration (AMD). METHODS: PubMed and Medline database searches were carried out using the terms "laser" and "photocoagulation" associated with "age-related macular degeneration", and latest publications up to May 2017 have been reviewed. Moreover, the design of an ongoing single-center, non-randomized, phase I-II, pilot study, the PASCAL-GA trial, coordinated by F. Bandello, MD and G. Querques, MD from the IRCCS Ospedale San Raffaele, is described. RESULTS: Either standard or subthreshold laser strategies have been tried to induce regression of distinct phenotypes of AMD, as reticular pseudodrusen (RPD), nascent geographic atrophy (nGA), and drusen-associated geographic atrophy (DAGA), with heterogeneous results. The aim of the PASCAL-GA protocol is to assess if subthreshold laser can restore the retinal pigment epithelium function in eyes with RPD and nGA offering a protective effect against extensive GA. CONCLUSIONS: New-generation medical and surgical approaches, including subthreshold laser photocoagulation, may have some success in downstaging AMD.

Web page:

https://doi.org/10.1007/s00417-017-3848-x

Product ID:

99991

Handle IRIS:

11562/972026

Last Modified:

November 15, 2022

Bibliographic citation:

Querques, Giuseppe; Cicinelli, Maria Vittoria; Rabiolo, Alessandro; de Vitis, Luigi; Sacconi, Riccardo; Querques, Lea; Bandello, Francesco, Laser photocoagulation as treatment of non-exudative age-related macular degeneration: state-of-the-art and future perspectives «Graefes Archive for Clinical and Experimental Ophthalmology» , vol. 256 , n. 1 , 2018 , pp. 1-9

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