Publications

Authors:

Sbrana, Francesco; Sozio, Emanuela; Bassetti, Matteo; Ripoli, Andrea; Pieralli, Filippo; Azzini, Anna Maria; Morettini, Alessandro; Nozzoli, Carlo; Merelli, Maria; Rizzardo, Sebastiano; Bertolino, Giacomo; Carrara, Davide; Scarparo, Claudio; Concia, Ercole; Menichetti, Francesco; Tascini, Carlo

Title:

Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

INTERNAL AND EMERGENCY MEDICINE

ISSN of journal:

1828-0447

N° Volume:

13

Number or Folder:

2

Page numbers:

199-204

Keyword:

Candidemia; Chronic kidney failure; Internal medicine wards; Sepsis; Septic shock; Steroid therapy

Short description of contents:

Candida is an increasing cause of bloodstream infection and is associated with significant morbidity and mortality. The aim of our study is to analyze risk factors for short-term mortality in patients with bloodstream Candida spp. infections admitted to Internal Medicine Wards (IMWs). This was a retrospective case-control study between January 2012 and December 2014 from four University Hospitals in Italy, where patients with candidemia dying within 30 days from diagnosis were matched to control cases with candidemia who survived in the same period of time. Two-hundred and fifty cases of candidemia were registered during the 36 months of enrollment. Among these, 112 patients died (45%) within 30 days from the first blood culture's positivity for Candida spp. At multivariate analysis, septic shock [odds ratio (95% CI) = 2.919 (1.62-5.35), p < 0.001] and concomitant chronic kidney failure [odds ratio (95% CI) = 2.296 (1.07-5.12), p = 0.036] were independent predictors of mortality. Low-dose chronic steroid therapy was protective [odds ratio (95% CI) = 0.461 (0.25-0.83), p = 0.011).

Product ID:

100079

Handle IRIS:

11562/972261

Last Modified:

November 15, 2022

Bibliographic citation:

Sbrana, Francesco; Sozio, Emanuela; Bassetti, Matteo; Ripoli, Andrea; Pieralli, Filippo; Azzini, Anna Maria; Morettini, Alessandro; Nozzoli, Carlo; Merelli, Maria; Rizzardo, Sebastiano; Bertolino, Giacomo; Carrara, Davide; Scarparo, Claudio; Concia, Ercole; Menichetti, Francesco; Tascini, Carlo, Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards «INTERNAL AND EMERGENCY MEDICINE» , vol. 13 , n. 2 , 2018 , pp. 199-204

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo