Publications

Reversibility of alexithymia with effective treatment of moderate-to-severe psoriasis: longitudinal data from EPIDEPSO  (2019)

Authors:
Sampogna, F; Puig, L; Spuls, P; Girolomoni, G; Radtke, Ma; Kirby, B; Brunori, M; Bergmans, P; Smirnov, P; Rundle, J; Castiglia, A; Lavie, F; Paul, C
Title:
Reversibility of alexithymia with effective treatment of moderate-to-severe psoriasis: longitudinal data from EPIDEPSO
Year:
2019
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Format:
A Stampa
Referee:
Name of journal:
British Journal of Dermatology
ISSN of journal:
0007-0963
N° Volume:
180
Page numbers:
397-403
Keyword:
alexithymia, moderate‐to‐severe psoriasis, EPIDEPSO
Short description of contents:
BACKGROUND: Alexithymia refers to difficulty in identifying and expressing emotions. Alexithymia is associated with high burden of disease in patients with psoriasis. OBJECTIVES: To investigate whether alexithymia was reversible in patients with psoriasis following real-life therapeutic intervention. METHODS: The Epidemiological Study in Patients with Recently Diagnosed Psoriasis (EPIDEPSO; NCT01964443) was a 1-year multicentre observational study investigating the prevalence of alexithymia and other psychosocial comorbidities in patients with psoriasis with ≤ 10 years' disease duration and eligible for systemic treatment. Alexithymia was assessed using the Toronto Alexithymia Scale (TAS-20) at baseline, 6 months and 1 year. RESULTS: There was a statistically significant decrease in the prevalence of alexithymia in the follow-up cohort, from 26·7% at baseline to 21·2% at 6 months and 18·8% at 1 year. More than half of the patients (n = 77, 53·8%) who were alexithymic at baseline experienced reversion of their alexithymia. Reversion of alexithymia was higher in patients who reached a high level of disease control, defined as ≥ 75% or ≥ 90% improvement in Psoriasis Area and Severity Index. Reversion of alexithymia was associated with dramatic improvement in quality of life, anxiety and depression. Moreover, hazardous alcohol use, highly prevalent in patients with alexithymia, was reduced almost threefold at 1 year. CONCLUSIONS: Alexithymia and associated high disease burden may be reversible in patients with effective treatment of psoriasis. Proactive recognition of patients who are unable to identify and express their feelings is importan
Product ID:
106743
Handle IRIS:
11562/991163
Last Modified:
August 18, 2019
Bibliographic citation:
Sampogna, F; Puig, L; Spuls, P; Girolomoni, G; Radtke, Ma; Kirby, B; Brunori, M; Bergmans, P; Smirnov, P; Rundle, J; Castiglia, A; Lavie, F; Paul, C, Reversibility of alexithymia with effective treatment of moderate-to-severe psoriasis: longitudinal data from EPIDEPSO «British Journal of Dermatology» , vol. 1802019pp. 397-403

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

<<back

Activities

Research facilities